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How IR-4 Works

To ensure that pest management tools you need are there when you need them, get involved.

  • Support your local extension agents, researchers and other agricultural experts, as they can help:
    • Identify the pest problem
    • Identify possible pest management solutions
  • Offer a corner of your field or greenhouse for a trial to evaluate possible management tools for your pest problem..
  • Continue to communicate your needs to local extension, your State Liaison Representative or the Northeast Regional Field Coordinator.

Submit a Project Clearance Request (PCR) ,or work with your local extension, researcher, State Liaison or Regional Field Coordinator on a PCR submission. This is VITALLY important because IR-4 cannot begin to help you without a PCR.

  • Anyone, growers, grower groups, agricultural extension or research workers, can submit a PCR, with the exception of chemical company representatives.
  • IR-4 does require application rate and timing information on the PCR.

The IR-4 process begins after the PCR has been received.

  • All new requests are reviewed by the manufacturer/registrant, to confirmation the company will add the use to their label, if a tolerance is established. The EPA also reviews project before research is started, to check for problems that might interfere with establishing a regulatory tolerance.
  • All active projects are prioritized by pest management experts once a year at the USDA/IR-4 Food Use Workshop. Research is started on Priority A projects that year and completed within 30 months. Priority B will be researched as money allows.
  • The research necessary to support the establishment of a regulatory tolerance is conducted.
  • In the field, the requested product is applied to the crop, and harvested, in manner that simulates proposed commercial usage. Trials are conducted across the U.S. in compliance with guidelines set by the U.S. EPA.
  • The raw agricultural commodity, and process products (when required) are analyzed for residues at IR-4 laboratories.
  • The field and laboratory data are sent to IR-4 Headquarters, where the data is summarized and submitted to the EPA.
  • The EPA evaluates the data package, conducts a risk assessment and establishes the tolerance. At that point, the registrant can add the new crop use to its product label for use by the growers.



IR-4 National HQ | North Central Regional IPM Center
Purdue University | College of Agriculture | Indiana Extension Service

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